Comparison between risk of bias-1 and risk of bias-2 tool and impact on network meta-analysis results—A case study from a living Cochrane review on psoriasis
The transition to RoB-2 in a large Cochrane SR revealed fair-to-moderate inter-rater agreement, underscoring the need for consensus among reviewers. The shift from RoB-1 to RoB-2 led to changes in risk-of-bias judgments in our review. Although the impact on the NMA results was pronounced for SAEs, the changes in results were limited for our efficacy outcome PASI 90.
Authors
- Quentin Samaran (ORCID: https://orcid.org/0000-0002-0560-5493)
- Quentin Beytout (ORCID: https://orcid.org/0000-0003-1905-0780)
- É. Sbidian (ORCID: https://orcid.org/0000-0002-1267-5270)
- Robin Guelimi (ORCID: https://orcid.org/0000-0002-4044-0727)
- Sivem Afach (ORCID: https://orcid.org/0000-0003-2791-223X)
- Cuckoo Choudhary
- Anna Chaimani (ORCID: https://orcid.org/0000-0003-2828-6832)
- L. Le Cleach
- C. Ollivier
- Alexia Mubuangankusu
Institutions
- University College Hospital (GB)
- University College London Hospitals NHS Foundation Trust (GB)
- Inserm (FR)
- Université Paris-Est Créteil (FR)
- Université de Montpellier (FR)
- Université Paris Cité (FR)
- Centre Hospitalier Universitaire Henri-Mondor (FR)
- Sorbonne Université (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Université Sorbonne Paris Nord (FR)
- Sorbonne Paris Cité (FR)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Hôpitaux Universitaires Henri-Mondor (FR)
- Centre de Recherche Épidémiologie et Statistique (FR)
- University College London (GB)
Publication Details
- Journal
- Journal of Clinical Epidemiology
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1016/j.jclinepi.2025.112097
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 0.00