An organ-on-a-chip investigation into dose-dependent, temporal dynamic effects of radiosurgery on the blood–brain barrier and its immunological response
Radiation effects on the BBB including barrier permeability and cytokine concentration can be observed in a dose- and time-dependent manner using an OOC.
Authors
- Cara Lwin (ORCID: https://orcid.org/0000-0001-9258-0302)
- Adam D. Yock (ORCID: https://orcid.org/0000-0003-3628-2380)
- John P. Wikswo (ORCID: https://orcid.org/0000-0003-2790-1530)
- Jacquelyn A. Brown (ORCID: https://orcid.org/0000-0002-2002-3010)
- John G. Eley (ORCID: https://orcid.org/0000-0002-8729-5088)
- Dandan Liu (ORCID: https://orcid.org/0000-0002-7176-8346)
Institutions
- Vanderbilt University (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Brain Research
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1016/j.brainres.2025.150092
- Citations
- 1
- Primary Topic
- Neuroscience and Neural Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.91