Plasma neurofilament light chain to evaluate response during cladribine treatment in multiple sclerosis
Cladribine significantly reduced pNfL levels, which stabilized at values comparable to matched healthy controls, confirming its strong efficacy with minimal disease activity during follow-up.
Authors
- G Corsini
- Marco Varelli
- Federica Novarella
- Mariano Fiorenza
- Daniela Terracciano (ORCID: https://orcid.org/0000-0003-4296-429X)
- Elena Cantone (ORCID: https://orcid.org/0000-0002-7389-2033)
- Cesare Polito
- Maria Petracca (ORCID: https://orcid.org/0000-0001-9429-2769)
- Roberta Lanzillo (ORCID: https://orcid.org/0000-0001-6388-8180)
- Antonio Carotenuto (ORCID: https://orcid.org/0000-0002-1574-9693)
- Stefania Fasano (ORCID: https://orcid.org/0000-0002-3696-7139)
- Evelina La Civita (ORCID: https://orcid.org/0000-0003-0543-9031)
- Marcello Moccia (ORCID: https://orcid.org/0000-0003-2613-3090)
- Valerio Nicolella (ORCID: https://orcid.org/0009-0009-0756-9877)
- Giuseppe Castaldo (ORCID: https://orcid.org/0000-0002-4036-0874)
- Vincenzo Brescia Morra (ORCID: https://orcid.org/0000-0003-0462-9618)
- Rosa Sirica (ORCID: https://orcid.org/0009-0006-3629-476X)
Institutions
- SDN Istituto di Ricerca Diagnostica e Nucleare (IT)
- Federico II University Hospital (IT)
- University of Naples Federico II (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Journal of the Neurological Sciences
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1016/j.jns.2025.125681
- Citations
- 2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94