Pattern of Failure Analysis and Clinical Outcomes in Patients with Grade 2 Meningiomas Following Radiation Therapy
This in-depth pattern of failure analysis for grade 2 meningiomas after radiation therapy demonstrated that treatment failures predominantly occur in close spatial relation to the irradiated target volume. Large treatment volumes, macroscopic disease, and a low EUD considerably impact disease control, underscoring the need for further local treatment and targeting refinements.
Authors
- Marc R. Bussière
- Andrzej Niemierko (ORCID: https://orcid.org/0000-0002-8895-5500)
- Helen Alice Shih (ORCID: https://orcid.org/0000-0003-1550-9726)
- Felix Ehret (ORCID: https://orcid.org/0000-0001-6177-1755)
- Grace Lee (ORCID: https://orcid.org/0000-0001-7592-7140)
- John A. Wolfgang
- Kevin Oh
Institutions
- Humboldt-Universität zu Berlin (DE)
- Massachusetts General Hospital (US)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- International Journal of Radiation Oncology*Biology*Physics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.ijrobp.2025.11.045
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Accuray
- Advanced Accelerator Applications
- Deutsche Krebshilfe
- Servier