Molecular basis of DNA cross-linking by bacteria

The structure of the bacterial genotoxin colibactin bound to DNA shows how it might contribute to cancer risk.

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Journal
Science
Published
2025-12-04
DOI
https://doi.org/10.1126/science.aec9205
Primary Topic
Escherichia coli research studies
Type
article
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article

Molecular basis of DNA cross-linking by bacteria

Orlando D. Schärer
Science
Escherichia coli research studies
article

Molecular basis of DNA cross-linking by bacteria

Orlando D. Schärer
article en

Abstract

The structure of the bacterial genotoxin colibactin bound to DNA shows how it might contribute to cancer risk.

ScienceVol. 390(6777)
UPMC Hillman Cancer Center (US)
Openalex Percentile: Top 67%
Escherichia coli research studies
DOISourceOpenAlex
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Molecular basis of DNA cross-linking by bacteria — Orlando D. Schärer · Science (2025) | TGRS Research Map | TGRS