Bone Health Index (BoneXpert) and parameters of peripheral quantitative computed tomography indicate overall adequate bone health in adolescents with chronic endocrine diseases at time of transition

At the time of transition, the bone health of adolescents with chronic endocrine diseases is mostly appropriate, as estimated by BoneXpertTM and pQCT. Grip strength was also adequate in the majority of patients. In addition, this study is the first to demonstrate a significant correlation between these methods in adolescents. Consequently, the BHI has the potential to be an effective screening tool for assessing bone health, characterized by wide availability and low radiation exposure, though additional analyses are needed.

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Publication Details

Journal
PLoS ONE
Published
2025-12-04
DOI
https://doi.org/10.1371/journal.pone.0337842
Primary Topic
Bone health and osteoporosis research
Type
article
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article

Bone Health Index (BoneXpert) and parameters of peripheral quantitative computed tomography indicate overall adequate bone health in adolescents with chronic endocrine diseases at time of transition

Johannes Hoos, Daniela Choukair, Markus Bettendorf, Sebastian Gippert
PLoS ONE
Bone health and osteoporosis research
article

Bone Health Index (BoneXpert) and parameters of peripheral quantitative computed tomography indicate overall adequate bone health in adolescents with chronic endocrine diseases at time of transition

Johannes Hoos, Daniela Choukair, Markus Bettendorf, Sebastian Gippert
article en

Abstract

At the time of transition, the bone health of adolescents with chronic endocrine diseases is mostly appropriate, as estimated by BoneXpertTM and pQCT. Grip strength was also adequate in the majority of patients. In addition, this study is the first to demonstrate a significant correlation between these methods in adolescents. Consequently, the BHI has the potential to be an effective screening tool for assessing bone health, characterized by wide availability and low radiation exposure, though additional analyses are needed.

PLoS ONEVol. 20(12)
Heidelberg University (DE), University Hospital Heidelberg (DE), Diabetesinstitut Heidelberg (DE)
Openalex Percentile: Top 52%
Bone health and osteoporosis research
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Bone Health Index (BoneXpert) and parameters of peripheral quantitative computed tomography indicate overall adequate bone health in adolescents with chronic endocrine diseases at time of transition — Johannes Hoos, Daniela Choukair, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS