Association of hydralazine use with risk of hematologic neoplasms in patients with hypertension: A nationwide population-based cohort study in Taiwan
In this study, we observed that long-term hydralazine use in patients with hypertension was associated with a lower, duration-dependent risk of hematologic neoplasms. These findings warrant prospective studies to confirm this association and its potential clinical implications.
Authors
- Bing-Heng Yang (ORCID: https://orcid.org/0000-0003-2902-632X)
- Chi‐Hsiang Chung (ORCID: https://orcid.org/0000-0002-4576-9900)
- Wu‐Chien Chien (ORCID: https://orcid.org/0000-0002-3286-0780)
- Yeu‐Chin Chen (ORCID: https://orcid.org/0000-0001-6751-7723)
- Li‐Tzu Wang (ORCID: https://orcid.org/0000-0003-1694-5263)
- Kevin Sheng‐Kai (ORCID: https://orcid.org/0000-0002-9394-4144)
- Weng-Sheng Tsai (ORCID: https://orcid.org/0000-0002-8293-9964)
Institutions
- Taiwan Nurses Association (TW)
- Taipei Medical University (TW)
- National Defense Medical Center (TW)
- University of Pennsylvania (US)
Publication Details
- Journal
- PLoS Medicine
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1371/journal.pmed.1004646
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00