Stability of arterial blood gas samples after delayed analysis and mechanical stress

Even after a 60-min delay and excessive mechanical stress, selected blood gas analytes such as hemoglobin, glucose, and electrolytes can be considered valid. Potassium and carbon dioxide partial pressure were altered but might be suitable for approximation purposes. Findings for oxygen partial pressure and lactate were generally invalid. In the future, these findings can aid in reducing unnecessary blood sampling. These findings may guide clinicians in deciding whether repeat sampling is necessary, potentially reducing unnecessary blood draws, while reinforcing that critical parameter (pO₂, pCO₂, pH) still require prompt analysis.

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Publication Details

Journal
PLoS ONE
Published
2025-12-04
DOI
https://doi.org/10.1371/journal.pone.0334710
Primary Topic
Clinical Laboratory Practices and Quality Control
Type
article
Field-Weighted Citation Impact
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article

Stability of arterial blood gas samples after delayed analysis and mechanical stress

Johannes Prottengeier, Andreas Moritz, Frederick Krischke, Max Gutermuth et al.
PLoS ONE
Clinical Laboratory Practices and Quality Control
article

Stability of arterial blood gas samples after delayed analysis and mechanical stress

Johannes Prottengeier, Andreas Moritz, Frederick Krischke, Max Gutermuth, Harald Ihmsen
article en

Abstract

Even after a 60-min delay and excessive mechanical stress, selected blood gas analytes such as hemoglobin, glucose, and electrolytes can be considered valid. Potassium and carbon dioxide partial pressure were altered but might be suitable for approximation purposes. Findings for oxygen partial pressure and lactate were generally invalid. In the future, these findings can aid in reducing unnecessary blood sampling. These findings may guide clinicians in deciding whether repeat sampling is necessary, potentially reducing unnecessary blood draws, while reinforcing that critical parameter (pO₂, pCO₂, pH) still require prompt analysis.

PLoS ONEVol. 20(12)
Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Klinikum Klagenfurt (AT), Universitätsklinikum Erlangen (DE), FMP Technology (Germany) (DE), University of Klagenfurt (AT)
Openalex Percentile: Top 52%
Clinical Laboratory Practices and Quality Control
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