Analysis of gene mutation spectrum for early-onset high myopia based on whole-exome sequencing
This study expands the eo-HM mutational spectrum and proposes novel HM pathogenic genes. PRS demonstrates a certain ability to predict eo-HM.
Authors
- M. Wang (ORCID: https://orcid.org/0009-0005-8523-8361)
- Xingtao Zhou (ORCID: https://orcid.org/0000-0002-3465-1579)
- Shilai Xing (ORCID: https://orcid.org/0000-0002-0869-1120)
- Dongmei Yang (ORCID: https://orcid.org/0000-0002-1351-3249)
- Zhanying Wang (ORCID: https://orcid.org/0000-0002-9885-8982)
- Liyin Wang
- Jing Zhao (ORCID: https://orcid.org/0009-0001-2450-4137)
- Xiaoguang Yu (ORCID: https://orcid.org/0009-0008-2818-8531)
- Yanze Yu
- Jian Cao (ORCID: https://orcid.org/0009-0006-7115-528X)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Second People's Hospital of Yunnan Province (CN)
- Shanghai Eye Disease Prevention & Treatment Center (CN)
- Eye & ENT Hospital of Fudan University (CN)
Publication Details
- Journal
- British Journal of Ophthalmology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1136/bjo-2025-327552
- Citations
- 1
- Primary Topic
- Ophthalmology and Visual Impairment Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Shanghai Municipal Health Commission