Physicochemical stability of the nefopam in elastomeric device at 0.2 and 3.33 mg/mL
The physicochemical stability of nefopam solutions at 0.2 and 3.33 mg/mL was demonstrated for 24 hours at 32°C in portable elastomeric infusion devices. This attribute allows continuous administration at home, particularly in cases of difficulty with oral administration, or minimises the side effects of discontinuous administration.
Authors
- Franck Blaise
- Nathalie Sobalak
- Jean Vigneron
- Pierre Le Quinio
- Marine Tambon (ORCID: https://orcid.org/0009-0000-9030-7011)
- Élise D’Huart
- Béatrice Demoré (ORCID: https://orcid.org/0000-0002-4196-0222)
- Caroline Marquet
- Aline Daval (ORCID: https://orcid.org/0009-0002-5649-1673)
Institutions
- Inserm (FR)
- ME Association (GB)
- Centre Hospitalier Universitaire de Toulouse (FR)
- Centre Hospitalier Régional et Universitaire de Nancy (FR)
- Centre d’Investigation Clinique Innovation Technologique de Nancy (FR)
- Interdisciplinarité en Santé Publique Interventions et Instruments de mesure complexes – Région Est (FR)
- Université de Lorraine (FR)
Publication Details
- Journal
- European Journal of Hospital Pharmacy
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1136/ejhpharm-2025-004668
- Primary Topic
- Intravenous Infusion Technology and Safety
- Type
- article
- Field-Weighted Citation Impact
- 0.00