Metabolic brain networks in dementia with Lewy bodies: from prodromal to manifest disease stages
This study demonstrates the value of DLBRP in diagnosing prodromal and manifest DLB and distinguishing them from their AD counterparts. While overlap between patterns may reflect actual co-pathology, this possibility cannot be accepted without thorough pathological confirmation. The current findings support the use of DLBRP in patient evaluation and in future trial design.
Authors
- Anette Davidsson (ORCID: https://orcid.org/0000-0001-5704-5670)
- Lourdes Álvarez‐Sánchez (ORCID: https://orcid.org/0000-0002-7016-9739)
- Valle Camacho (ORCID: https://orcid.org/0000-0003-0748-0847)
- Andrea Pilotto (ORCID: https://orcid.org/0000-0003-2029-6606)
- Afina W. Lemstra (ORCID: https://orcid.org/0000-0002-8933-3260)
- Daniel Ferreira (ORCID: https://orcid.org/0000-0001-9522-4338)
- Valentina Garibotto (ORCID: https://orcid.org/0000-0003-2422-698X)
- Jan Jamšek (ORCID: https://orcid.org/0000-0002-6323-8767)
- Philipp T. Meyer (ORCID: https://orcid.org/0000-0001-8336-750X)
- Ji Hyun Ko (ORCID: https://orcid.org/0000-0002-9700-7692)
- David Eidelberg (ORCID: https://orcid.org/0000-0002-0854-864X)
- Anna Stockbauer
- Chong Sik Lee (ORCID: https://orcid.org/0000-0002-3474-0440)
- Matthias Brendel (ORCID: https://orcid.org/0000-0002-9247-2843)
- M.A. Ochoa-Figueroa (ORCID: https://orcid.org/0000-0001-9444-8225)
- Urban Simončič (ORCID: https://orcid.org/0000-0002-5835-072X)
- Consuelo Cháfer‐Pericás (ORCID: https://orcid.org/0000-0002-0711-5877)
- Joachim Brumberg (ORCID: https://orcid.org/0000-0003-0959-4776)
- Silvia Paola Caminiti
- Matteo Pardini (ORCID: https://orcid.org/0000-0002-4740-1982)
- Rik R. Vandenberghe (ORCID: https://orcid.org/0000-0001-6237-2502)
- Daniela Perani (ORCID: https://orcid.org/0000-0002-9784-292X)
- Koen Van Laere (ORCID: https://orcid.org/0000-0001-5200-7245)
- Silvia Morbelli (ORCID: https://orcid.org/0000-0002-7833-6095)
- Milica Gregorič Kramberger (ORCID: https://orcid.org/0000-0001-8231-1176)
- Daniel Alcolea (ORCID: https://orcid.org/0000-0002-3819-3245)
- Matej Perovnik (ORCID: https://orcid.org/0000-0001-8595-7773)
- Alessandro Padovani (ORCID: https://orcid.org/0000-0002-0119-3639)
- Chris C. Tang
- Maja Trošt
- Lorenzo Lombardo (ORCID: https://orcid.org/0009-0009-4251-0512)
Institutions
- Linköping University (SE)
- University of Geneva (CH)
- Northwell Health (US)
- Feinstein Institute for Medical Research (US)
- University of Ljubljana (SI)
- Vita-Salute San Raffaele University (IT)
- University of Freiburg (DE)
- University of Pavia (IT)
- University Medical Center Freiburg (DE)
- Ljubljana University Medical Centre (SI)
- German Center for Neurodegenerative Diseases (DE)
- Hospital de Sant Pau (ES)
- Karolinska Institutet (SE)
- LMU Klinikum (DE)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Universidad Fernando Pessoa Canarias (ES)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Amsterdam Neuroscience (NL)
- Munich Cluster for Systems Neurology (DE)
- CHA University Bundang Medical Center (KR)
- CHA University (KR)
- Linköping University Hospital (SE)
- Instituto de Investigación Sanitaria La Fe (ES)
- University of Manitoba (CA)
- University of Turin (IT)
- Geneva College (US)
- University of Brescia (IT)
- Ludwig-Maximilians-Universität München (DE)
- University of Genoa (IT)
- KU Leuven (BE)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1136/jnnp-2025-336935
- Primary Topic
- Neurological and metabolic disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Genova
- Dipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli Federico II