Clonal Hematopoiesis and Kidney Function in the ASPREE Cohort

We propose that the effect of CHIP is modified by participant factors, including comorbidities, partly accounting for heterogeneity across cohorts. This work contributes to a growing understanding of the interplay between CHIP and disease, and considerations in translating findings from large observational studies to individuals with CHIP.

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Publication Details

Journal
Kidney International Reports
Published
2025-12-04
DOI
https://doi.org/10.1016/j.ekir.2025.11.037
Primary Topic
Myeloproliferative Neoplasms: Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Clonal Hematopoiesis and Kidney Function in the ASPREE Cohort

Paul Lacaze, Kevan R. Polkinghorne, Jasmine Singh, Sean Byars et al.
Kidney International Reports
Myeloproliferative Neoplasms: Diagnosis and Treatment
article

Clonal Hematopoiesis and Kidney Function in the ASPREE Cohort

Paul Lacaze, Kevan R. Polkinghorne, Jasmine Singh, Sean Byars, Lê Thị Phương Thảo, Anna Leichter, Hayley S. Ramshaw, James B. Wetmore, Erica M. Wood, Robyn L. Woods, John J. McNeil, James Phung, Rory Wolfe, Nicholas C. Wong, Suzanne Gaye Orchard, Zoe McQuilten, David J. Curtis
article en

Abstract

We propose that the effect of CHIP is modified by participant factors, including comorbidities, partly accounting for heterogeneity across cohorts. This work contributes to a growing understanding of the interplay between CHIP and disease, and considerations in translating findings from large observational studies to individuals with CHIP.

Kidney International ReportsVol. 11(2)
Fiona Stanley Hospital (AU), Monash Health (AU), Australian Centre for HIV and Hepatitis Virology Research (AU), Hennepin Healthcare Research Institute (US), Alfred Health (AU), Monash University (AU)
Openalex Percentile: Top 45%
Myeloproliferative Neoplasms: Diagnosis and Treatment
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