Dominance of IL-5 and CCL17 in nasal cytokine profiles of children with type 2 inflammation
Nasal epithelial lining fluid sampling is a valuable, noninvasive, and airway-specific tool for immunophenotyping T2 inflammation in 6-year-old children. Nasal IL-5 and CCL17 are consistent biomarkers of T2 inflammation and disease.
Authors
- Jonathan Thorsen (ORCID: https://orcid.org/0000-0003-0200-0461)
- Klaus Bønnelykke (ORCID: https://orcid.org/0000-0003-2003-1018)
- Julie Nyholm Kyvsgaard (ORCID: https://orcid.org/0000-0002-8089-861X)
- Bo Chawes (ORCID: https://orcid.org/0000-0001-6846-6243)
- Ann‐Marie Malby Schoos (ORCID: https://orcid.org/0000-0002-5827-0885)
- Laura Marie Hesselberg
- Tamo Sultan (ORCID: https://orcid.org/0009-0006-6049-1683)
- Frederikke Skov
- Nicklas Brustad (ORCID: https://orcid.org/0000-0001-6383-8845)
- Susanne Brix (ORCID: https://orcid.org/0000-0001-8951-6705)
- Nilo Vahman (ORCID: https://orcid.org/0009-0005-3604-2602)
- Anton Kjellberg
Institutions
- Copenhagen Prospective Studies on Asthma in Childhood (DK)
- Technical University of Denmark (DK)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.jaci.2025.11.009
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00