Burn injuries in the Asia-Pacific region: Use of polyhexamethylene biguanide and betaine surfactant (PHMB-B) for wound bed preparation in children and adults
This case-series supplement serves as an educational resource for health professionals involved in the care of burn injuries. Drawing from clinical experiences across healthcare settings in the Asia-Pacific region, the supplement focuses on the use of polyhexamethylene biguanide and betaine surfactant (PHMB-B) solution, gel and high-viscosity gel, alone or in combination, in managing both thermal and non-thermal burns, including partial-thickness and full-thickness burns, in both paediatric and adult populations. In alignment with international guidance, this supplement reinforces the recommendation to integrate PHMB-B into routine practice. The broad-spectrum antimicrobial activity, low cytotoxicity and biofilm-disruptive properties of this combined solution is clinically appropriate for use in complex burn wounds, where infection control and optimal healing conditions are crucial to wound healing.
Authors
- Ricardo Santamarı́a (ORCID: https://orcid.org/0000-0001-9818-6998)
- Amelia Ganefianty (ORCID: https://orcid.org/0000-0003-3303-1519)
- Suttipong Tianwattanatada
- Gerald Marion M Abesamis (ORCID: https://orcid.org/0000-0002-0602-325X)
- Mohd Shahrul Suondoh
- Nan An (ORCID: https://orcid.org/0009-0001-6240-4719)
- Yi Dou (ORCID: https://orcid.org/0000-0003-3725-4357)
- Suchada Kittidacha
- Chenlu Song (ORCID: https://orcid.org/0000-0003-3499-2872)
- Xuechuan Li (ORCID: https://orcid.org/0009-0004-5745-3710)
- Wandong Wang (ORCID: https://orcid.org/0000-0002-6610-0368)
- Salmi Mohamed Sukur
- Anchan Ketmek
- Zhinan Yin (ORCID: https://orcid.org/0000-0001-6524-8777)
- Yan Liu (ORCID: https://orcid.org/0000-0002-8193-6729)
- Gai Zhang (ORCID: https://orcid.org/0000-0003-0418-0689)
- Huizhong Yang (ORCID: https://orcid.org/0000-0003-4522-0042)
- Min Gao (ORCID: https://orcid.org/0000-0002-8253-0587)
- Gayan Ekanayake (ORCID: https://orcid.org/0000-0002-0839-4935)
- Harikrishna KR Nair
- Pornprom Muangman
- Abdel Hakim
- Jin Zhu
- Kerrie Coleman
- Deni Alia Yadi
- Orapin Taengthet
- Chamath Sachindra Angulugaha
- SVP Wimalarathna
- Fernando A Acance
- Wipawee Kanpuan
- Duong Van Phu
- Claudine Rosario B Lukban
- Thanchanock Sawangsangwattana
- Tippawan Wattanakham
- Amarmend Ganbat
Institutions
- Siriraj Hospital (TH)
- Hospital Kuala Lumpur (MY)
- Bangkok Metropolitan Administration (TH)
- Ruijin Hospital (CN)
- Philippine General Hospital (PH)
- Mongolian National University (MN)
- National Center for Communicable Diseases (MN)
- Dr. Hasan Sadikin General Hospital (ID)
- National Hospital of Sri Lanka (LK)
- Wound Healing Society (US)
- Vietnam National Children's Hospital (VN)
- Nakornping Hospital (TH)
- National University of Mongolia (MN)
- American Association of Nurse Practitioners (US)
Publication Details
- Journal
- Journal of Wound Care
- Published
- 2025-12-01
- DOI
- https://doi.org/10.12968/jowc.2025.34.sup12c.s1
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00