Label-Driven Optimization of Trading Models Across Indices and Stocks: Maximizing Percentage Profitability

Short-term trading presents a high-dimensional prediction problem, where the profitability of trading signals depends not only on model accuracy but also on how financial labels are defined and aligned with market dynamics. Traditional approaches often apply uniform modeling choices across assets, overlooking the asset-specific nature of volatility, liquidity, and market response. In this work, we introduce a structured, label-aware machine learning pipeline aimed at maximizing short-term trading profitability across four major benchmarks: S&P 500 (SPX), NASDAQ-100 (NDX), Dow Jones Industrial Average (DJI), and the Tadāwul All-Share Index (TASI and twelve of their most actively traded constituents). Our solution systematically evaluates all combinations of six model types (logistic regression, support vector machines, random forest, XGBoost, 1-D CNN, and LSTM), eight look-ahead labeling windows (3 to 10 days), and four feature subset sizes (44, 26, 17, 8 variables) derived through Random Forest permutation-importance ranking. Backtests are conducted using realistic long/flat simulations with zero commission, optimizing for Percentage Profit and Profit Factor on a 2005–2021 train/2022–2024 test split. The central contribution of the framework is a labeling-aware search mechanism that assigns to each asset its optimal combination of model type, look-ahead horizon, and feature subset based on out-of-sample profitability. Empirical results show that while XGBoost performs best on average, CNN and LSTM achieve standout gains on highly volatile tech stocks. The optimal look-ahead window varies by market from 3-day signals on liquid U.S. shares to 6–10-day signals on the less-liquid TASI universe. This joint model–label–feature optimization avoids one-size-fits-all assumptions and yields transferable configurations that cut grid-search cost when deploying from index level to constituent stocks, improving data efficiency, enhancing robustness, and supporting more adaptive portfolio construction in short-horizon trading strategies.