Postauthorization Safety Study (NISSO) Assessing the Long-Term Safety Profile of Sonidegib in Patients With Locally Advanced Basal Cell Carcinoma: Interim Analysis From the Spanish Cohort
Most patients experienced grade≤2 common TEAEs, such as muscle spasms, dysgeusia, and alopecia that mostly manifested 3 months into therapy. These interim results confirm the safety profile observed in the BOLT study, demonstrating that sonidegib is well-tolerated in a real-world setting in Spain.
Authors
- M.J. Fuente (ORCID: https://orcid.org/0000-0002-9050-8611)
- V. Ruiz-Salas
- Ángeles Flórez (ORCID: https://orcid.org/0000-0001-9373-7826)
- Gabriela Pastor
- Matías Mayor Arenal (ORCID: https://orcid.org/0000-0003-2161-5082)
- Josep Malvehy (ORCID: https://orcid.org/0000-0002-6998-914X)
- Renate M. Arntz (ORCID: https://orcid.org/0009-0008-1785-4551)
- Patricia Bassas-Freixas
- Ricardo Fernández‐de‐Misa (ORCID: https://orcid.org/0000-0003-4120-9962)
- Rafael Botella Estrada
- Perla Almazan
- S. Bèa Ardébol
Institutions
- Hospital Universitario La Paz (ES)
- Hospital de Sant Pau (ES)
- Hospital Universitari i Politècnic La Fe (ES)
- Hospital Universitario Nuestra Señora de Candelaria (ES)
- Hospital Universitario de Gran Canaria Doctor Negrín (ES)
- Hospital Clínic de Barcelona (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Hospital General Universitario De Valencia (ES)
- Hospital Universitari Germans Trias i Pujol (ES)
- Complejo Hospitalario de Pontevedra (ES)
- Hospital Universitario Ramón y Cajal (ES)
Publication Details
- Journal
- Actas Dermo-Sifiliográficas
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1016/j.ad.2025.104524
- Primary Topic
- Nonmelanoma Skin Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00