Close V, Close W, Kugler SJ, et al. <i>FBXW7</i> mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL. <i>Blood</i> . 2019;133(8):830-839.

On page 835, the western blot at the bottom of Figure 5B is a duplicate copy of the western blot at the bottom of Figure 5C.In the description of Figure 5B in the figure legend, "Lane 8: expression control for FBXW7, lysate from FBXW7 transfected cells, no-CoIP" should read "Lane 8: lysate from untransfected cells, no-CoIP."The authors have inserted the correct blot at the bottom of Figure 5B, and the corrected Figure 5 and legend are shown below.This error does not affect the results or the conclusions of the study.

Publication Details

Journal
Blood
Published
2025-12-04
DOI
https://doi.org/10.1182/blood.2025031881
Primary Topic
Cerebrovascular and genetic disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Close V, Close W, Kugler SJ, et al. FBXW7 mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL. Blood . 2019;133(8):830-839.

Blood
Cerebrovascular and genetic disorders
article

Close V, Close W, Kugler SJ, et al. FBXW7 mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL. Blood . 2019;133(8):830-839.

article en

Abstract

On page 835, the western blot at the bottom of Figure 5B is a duplicate copy of the western blot at the bottom of Figure 5C.In the description of Figure 5B in the figure legend, "Lane 8: expression control for FBXW7, lysate from FBXW7 transfected cells, no-CoIP" should read "Lane 8: lysate from untransfected cells, no-CoIP."The authors have inserted the correct blot at the bottom of Figure 5B, and the corrected Figure 5 and legend are shown below.This error does not affect the results or the conclusions of the study.

BloodVol. 146(23)
Openalex Percentile: Top 47%
Cerebrovascular and genetic disorders
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Close V, Close W, Kugler SJ, et al. <i>FBXW7</i> mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL. <i>Blood</i> . 2019;133(8):830-839. · Blood (2025) | TGRS Research Map | TGRS