Challenges in Diagnosis and Management of Complex Regional Pain Syndrome: Insights From a Retrospective 9-Year Review in an Academic Medical Center

Standardized diagnostic criteria and early occupational therapy engagement were associated with improved documentation. Future research should explore the role of rehabilitation in CRPS care. Plain-Language Summary: This study examined how complex regional pain syndrome is diagnosed and treated, with a focus on its effects on daily activities and how early intervention can improve recovery. Complex regional pain syndrome is a painful condition that can develop after an injury, leading to challenges with movement and participation in everyday tasks. Researchers analyzed medical records to understand how often doctors used the Budapest Criteria, the standard guidelines for diagnosing complex regional pain syndrome, and found that, in many cases, the criteria were not properly documented, which may lead to diagnostic uncertainty. The study also emphasized the importance of rehabilitation, especially occupational therapy and physical therapy, as the first step in treatment, followed by medications if symptoms persisted. These findings underscore the need for consistent diagnostic practices and early occupational therapy engagement to support function and recovery in people with complex regional pain syndrome.