Lightweight UNet with multi-module synergy and dual-domain attention for precise skin lesion segmentation
Skin cancer poses a significant threat to life, necessitating early detection. Skin lesion segmentation, a critical step in diagnosis, remains challenging due to variations in lesion size and edge blurring. Despite recent advancements in computational efficiency, edge detection accuracy remains a bottleneck. In this paper, we propose a lightweight UNet with multi-module synergy and dual-domain attention for precise skin lesion segmentation to address these issues. Our model combines the Swin Transformer (Swin-T) block, Multi-Axis External Weighting (MEWB), Group multi-axis Hadamard Product Attention (GHPA), and Group Aggregation Bridge (GAB) within a lightweight framework. Swin-T reduces complexity through parallel processing, MEWB incorporates frequency domain information for comprehensive feature capture, GHPA extracts pathological information from diverse perspectives, and GAB enhances multi-scale information extraction. On the ISIC2017 and ISIC2018 datasets, our model achieves mIoU and DSC scores of 81.22% and 89.64%, and 81.65% and 89.90%, respectively. These results demonstrate improved segmentation accuracy with low parameter count and computational cost, aiding physicians in diagnosis and treatment. https://github.com/SolitudeWolf/ESMDL-UNet.git.
Authors
- Chang‐Hua Chen (ORCID: https://orcid.org/0000-0003-4564-8727)
- Yanjie You (ORCID: https://orcid.org/0000-0001-6064-691X)
- Ling Li (ORCID: https://orcid.org/0000-0001-9722-9503)
- Jiayi Li (ORCID: https://orcid.org/0000-0003-1691-9743)
- Chao Zhang (ORCID: https://orcid.org/0000-0002-1018-4144)
- Bin Yu (ORCID: https://orcid.org/0000-0002-1862-5936)
- Bo Li (ORCID: https://orcid.org/0000-0002-3345-8339)
- Wei Zhou (ORCID: https://orcid.org/0009-0008-3171-1506)
- Haijun Li (ORCID: https://orcid.org/0009-0002-9143-6653)
- Zhuo Wang (ORCID: https://orcid.org/0009-0002-2315-8604)
Institutions
- Xihua University (CN)
- First Affiliated Hospital of Sichuan Medical University (CN)
- Neijiang Normal University (CN)
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
- The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1038/s41598-025-28088-1
- Primary Topic
- Cutaneous Melanoma Detection and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00