Direct thrombectomy versus bridging alteplase medicine in anterior circulation stroke following endovascular therapy: a multi-center cohort study
Pre-EVT rt-PA did not improve functional outcomes or reduce mortality in AIS patients. While rt-PA showed a trend toward higher reperfusion rates, this did not translate to clinical benefit. Hemorrhage risks were similar between groups.
Authors
- Shuiquan Yang (ORCID: https://orcid.org/0000-0001-8192-4130)
- Zhiwei Xu (ORCID: https://orcid.org/0000-0001-7903-2141)
- Lue Chen (ORCID: https://orcid.org/0000-0001-7658-5787)
- Xiaofeng Lin (ORCID: https://orcid.org/0000-0002-4596-2196)
- Mingzhu Feng
- Mohammad Mofatteh (ORCID: https://orcid.org/0000-0002-2458-0447)
- Zile Yan
- Wenhong Peng
- Yuzheng Lai
- Sijie Zhou
- Haiping Wang
- Jicai Ma
- Xue-Hua Zeng
- Yi Jian (ORCID: https://orcid.org/0000-0001-9574-8043)
- Minhua Zhou
Institutions
- Queen's University Belfast (GB)
- Shaoguan University (CN)
- Shantou University (CN)
- Panyu Hospital of Chinese Medicine (CN)
- The First People's Hospital of Shunde (CN)
- Foshan Hospital of TCM (CN)
- First People's Hospital of Foshan (CN)
- Yue Bei People's Hospital (CN)
- Shantou University Medical College (CN)
- Zhujiang Hospital (CN)
- Panyu District Central Hospital (CN)
- Shaoguan Railway Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1186/s40001-025-03591-3
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00