Applying the Lasso Model to Identify Risk Factors for Piperacillin-Tazobactam-Induced Leukopenia
Clinicians should recognize the potential association between TZP administration and leukopenia. Routine hematologic monitoring should emphasize leukocyte trends to assess both therapeutic response and drug safety.
Authors
- Fang Zheng (ORCID: https://orcid.org/0000-0002-2024-2424)
- Xiaohui Liu (ORCID: https://orcid.org/0000-0002-8983-4567)
- Xuefeng Yuan (ORCID: https://orcid.org/0009-0003-0098-7538)
- Jiheng Liu (ORCID: https://orcid.org/0000-0002-1310-6707)
- Lihua Liu (ORCID: https://orcid.org/0000-0001-6696-7538)
- Long Wen (ORCID: https://orcid.org/0000-0003-1577-3017)
Institutions
- Central South University (CN)
- The First Hospital of Changsha (CN)
- Xiangya Hospital Central South University (CN)
- Third Hospital of Changsha (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/dddt.s544195
- Primary Topic
- Blood disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00