50-Year age threshold for early-onset NSCLC: A SEER-TCGA retrospective analysis reveals a prognostic paradox based on age treatment response
The age threshold for optimal differentiation between patients with EOLC and LOLC is 50 years, Patients with EOLC benefit from aggressive surgery and age-dependent treatment, supported by treatment efficacy and molecular heterogeneity.
Authors
- Keyu Zhu (ORCID: https://orcid.org/0000-0003-0351-7155)
- Xinyan Huang (ORCID: https://orcid.org/0000-0002-0584-8452)
- Jingrong Yang (ORCID: https://orcid.org/0009-0008-1722-6061)
- Yiyang Chen (ORCID: https://orcid.org/0000-0001-9960-9040)
- Haiyan Wang (ORCID: https://orcid.org/0009-0001-7246-431X)
- Zhixin Lin (ORCID: https://orcid.org/0009-0009-4710-2024)
- Yu Wang (ORCID: https://orcid.org/0000-0002-5578-6827)
- Yi Liao (ORCID: https://orcid.org/0000-0003-2454-8532)
- Zheng Lu
- Peilan Zheng
Institutions
- Fujian Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1097/js9.0000000000003770
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00