Alterations in white matter microstructure and glymphatic function in post-traumatic disorders of consciousness: impact on consciousness levels and prognosis

This study suggested that TBI may cause brain structural damage, impair glymphatic function, and subsequently affect patients' levels of consciousness. These findings further indicate that glymphatic dysfunction could play an important role in the pathogenesis and prognosis of DoCs.

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Publication Details

Journal
Neuroreport
Published
2025-12-03
DOI
https://doi.org/10.1097/wnr.0000000000002235
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00
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article

Alterations in white matter microstructure and glymphatic function in post-traumatic disorders of consciousness: impact on consciousness levels and prognosis

Jing Zhang, Wenjing Huang, Dan Yang, Minglian Da et al.
Neuroreport
Cerebrospinal fluid and hydrocephalus
article

Alterations in white matter microstructure and glymphatic function in post-traumatic disorders of consciousness: impact on consciousness levels and prognosis

Jing Zhang, Wenjing Huang, Dan Yang, Minglian Da, Xiaoyang Ma, Xiaoling Li, Zhuo Wang, Jiahao Yan
article en

Abstract

This study suggested that TBI may cause brain structural damage, impair glymphatic function, and subsequently affect patients' levels of consciousness. These findings further indicate that glymphatic dysfunction could play an important role in the pathogenesis and prognosis of DoCs.

NeuroreportVol. 37(1)
Changzhi Medical College (CN), Lanzhou University Second Hospital (CN), Lanzhou University (CN)
Openalex Percentile: Top 59%
Cerebrospinal fluid and hydrocephalus
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