Supramolecular assembly of an organoplatinum( <scp>ii</scp> ) complex boosts intersystem crossing for potentiated photocatalytic therapy and disulfidptosis
PtATPA, a self-assembling Pt( ii ) complex, forms nanostructures via Pt⋯Pt/π–π interactions, boosting photophysics for enhanced PCT. In A549 cells, it triggers oxidative stress-induced disulfidptosis, offering a metal-complex strategy to advance PCT.
Authors
- Xiaoting Liang (ORCID: https://orcid.org/0000-0003-3262-1859)
- Pingyu Zhang (ORCID: https://orcid.org/0000-0002-2921-9490)
- Bole Yu (ORCID: https://orcid.org/0009-0005-7040-7943)
- Guotao Yuan (ORCID: https://orcid.org/0000-0002-0584-0653)
- Dan Li (ORCID: https://orcid.org/0000-0001-5904-871X)
- Zhaoyang Liu (ORCID: https://orcid.org/0000-0001-7972-3452)
- Hanqiang Wang (ORCID: https://orcid.org/0009-0000-6197-2610)
- Xintong Lin
- Haitao Ma (ORCID: https://orcid.org/0000-0002-8930-614X)
Institutions
- Shenzhen University (CN)
- Great Bay University
Publication Details
- Journal
- Inorganic Chemistry Frontiers
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1039/d5qi02189h
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00