Changes in cerebral oxygenation during sit-to-stand test in COPD patients compared to controls and the effect of oxygen supplementation

<title>Extract</title> Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity, mortality, and disability worldwide. While it is primarily characterized by persistent, non-fully reversible airflow limitation, COPD is now recognized as a systemic disease with extrapulmonary manifestations [1]. Among these, impaired functional performance -reflected in difficulty standing from a seated position, stair climbing or fast walking for everyday chores- leads to higher fall risk, reduced independence, and poorer quality of life [2]. Importantly, these deficits often occur even in the absence of resting hypoxemia. Contributing factors include skeletal muscle weakness, impaired balance and coordination [3].

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Publication Details

Journal
ERJ Open Research
Published
2025-12-04
DOI
https://doi.org/10.1183/23120541.00955-2025
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
Field-Weighted Citation Impact
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article

Changes in cerebral oxygenation during sit-to-stand test in COPD patients compared to controls and the effect of oxygen supplementation

Georgia Pitsiou, Κωνσταντίνα Δίπλα, Pantelis Sarafidis, Aggelos Koutlas et al.
ERJ Open Research
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Changes in cerebral oxygenation during sit-to-stand test in COPD patients compared to controls and the effect of oxygen supplementation

Georgia Pitsiou, Κωνσταντίνα Δίπλα, Pantelis Sarafidis, Aggelos Koutlas, Marieta P. Theodorakopoulou, Andreas Zafeiridis, Stella Kritikou, Afroditi Boutou, Aikaterini Gakidi, Leonidas Kastritseas, Rafaella Emmanouilidou
article en

Abstract

<title>Extract</title> Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity, mortality, and disability worldwide. While it is primarily characterized by persistent, non-fully reversible airflow limitation, COPD is now recognized as a systemic disease with extrapulmonary manifestations [1]. Among these, impaired functional performance -reflected in difficulty standing from a seated position, stair climbing or fast walking for everyday chores- leads to higher fall risk, reduced independence, and poorer quality of life [2]. Importantly, these deficits often occur even in the absence of resting hypoxemia. Contributing factors include skeletal muscle weakness, impaired balance and coordination [3].

ERJ Open Research
University of Thessaly (GR), Aristotle University of Thessaloniki (GR), General Hospital of Serres (GR), Ippokrateio General Hospital of Thessaloniki (GR), G. Papanikolaou General Hospital (GR), Hippocration General Hospital (GR)
Openalex Percentile: Top 43%
Chronic Obstructive Pulmonary Disease (COPD) Research
DOIOpen Access PDFOpenAlex
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Changes in cerebral oxygenation during sit-to-stand test in COPD patients compared to controls and the effect of oxygen supplementation — Georgia Pitsiou, Κωνσταντίνα Δίπλα, et al. · ERJ Open Research (2025) | TGRS Research Map | TGRS