Polypeptide Nanomicrospheres Delivering Dexmedetomidine Mitigate Intestinal Ischemia/Reperfusion Injury by Regulating Autophagy and Inflammation
PNM@Dex effectively alleviated intestinal I/R-induced damage through autophagy induction, oxidative stress reduction, and inflammation modulation, underscoring its promise as a therapeutic strategy for intestinal protection and transplantation. <i>Antioxid. Redox Signal.</i> 44, 213-235.
Authors
- Qiuhong Chen (ORCID: https://orcid.org/0009-0006-8625-5283)
- Jinping Nie (ORCID: https://orcid.org/0000-0003-0711-3545)
- Chenlu Fan
- Sisi Liang
- Zhen Liu (ORCID: https://orcid.org/0009-0007-9034-2969)
- Qin Zhang (ORCID: https://orcid.org/0000-0002-6565-190X)
- Qian Hu (ORCID: https://orcid.org/0009-0000-6985-263X)
- Qiong Wu (ORCID: https://orcid.org/0000-0002-1653-3683)
- Xuekang Zhang
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Antioxidants and Redox Signaling
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1177/15230864251394744
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00