Oral corticosteroid overexposure: characterizing oral corticosteroid use in patients with chronic rhinosinusitis with nasal polypS in Canada (ACTIONS) results
This study highlights OCS overexposure in patients with CRSwNP pre-biologic initiation. Enhancing physician and patient awareness of appropriate OCS use and timely biologic initiation could reduce the risk of OCS-related adverse effects and improve CRSwNP management, benefiting long-term patient outcomes through shared decision-making. Trial registration GSK study number 221872.
Authors
- Ali Reza Tehrani‐Bagha (ORCID: https://orcid.org/0000-0002-8206-3827)
- Juejing Ling (ORCID: https://orcid.org/0000-0002-4383-713X)
- Jenna Reynolds (ORCID: https://orcid.org/0000-0003-1591-3681)
- Andrew Thamboo (ORCID: https://orcid.org/0000-0002-3910-2253)
- Koyo Usuba (ORCID: https://orcid.org/0000-0002-8850-2341)
- Huijuan Yang (ORCID: https://orcid.org/0000-0003-4569-6454)
- Danya Thayaparan
- Yvonne Chan (ORCID: https://orcid.org/0000-0002-8502-3214)
- Marie-Noëlle Corriveau
- Jeffrey Beach
Institutions
- IQVIA (United Kingdom) (GB)
- GlaxoSmithKline (Canada) (CA)
- Université Laval (CA)
Publication Details
- Journal
- Allergy Asthma and Clinical Immunology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1186/s13223-025-00989-w
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00