Integrated bulk and single-cell transcriptomics to develop an efferocytosis-related prognostic model for lung adenocarcinoma and validate the key gene LDHA
We constructed an efferocytosis-related prognostic gene model for LUAD. Furthermore, LDHA may target M2 macrophages, highlighting its potential as a therapeutic target in LUAD.
Authors
- Benyuan Sun (ORCID: https://orcid.org/0009-0000-0003-8824)
- Mingxi Wang (ORCID: https://orcid.org/0000-0002-8093-0384)
- Qing Chen (ORCID: https://orcid.org/0000-0002-9019-9230)
- Yue Li (ORCID: https://orcid.org/0000-0002-1163-3634)
- Li Zhang (ORCID: https://orcid.org/0000-0003-1620-1512)
- Haiying Dong
- Weipeng Zhang (ORCID: https://orcid.org/0000-0002-1231-8927)
- Fan Yang (ORCID: https://orcid.org/0000-0001-7543-7328)
- Shuo Yang (ORCID: https://orcid.org/0000-0002-6834-4905)
Institutions
- Qiqihar Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1186/s40001-025-03622-z
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00