FGF21 inhibits invasion and metastasis via IL-17A-Notch in pancreatic ductal adenocarcinoma
FGF21 suppresses invasion and metastasis in PDAC by inhibiting the IL-17A-Notch signaling axis, which reveals a novel therapeutic strategy for this malignancy.
Authors
- Hangyu Zhou (ORCID: https://orcid.org/0000-0002-3762-2319)
- Yaying Yang (ORCID: https://orcid.org/0000-0002-8901-3427)
- F. Li
- Xiongwu Li
- Panchun Zheng
- Linjun Li
Institutions
- Chongqing University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Emergency Medical Center (CN)
- First People's Hospital of Chongqing (CN)
- Chongqing Dazu District People's Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.3389/fonc.2025.1680888
- Primary Topic
- Fibroblast Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00