Liver Stiffness Characterization of <scp> OGT <sup>LKO</sup> </scp> Mouse Model of Progressive Liver Fibrosis

Our study confirms that following liver stiffness fibrosis by SWE in a mouse model of liver injury is a valuable tool that correlates with ex vivo findings. This approach facilitates a better understanding of disease progression and therapeutic evaluation in preclinical models of MASH.

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Publication Details

Journal
Journal of Ultrasound in Medicine
Published
2025-12-04
DOI
https://doi.org/10.1002/jum.70146
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Liver Stiffness Characterization of OGT LKO Mouse Model of Progressive Liver Fibrosis

Marion Régnier, Jean‐Luc Gennisson, Anthony Novell, R Denis et al.
Journal of Ultrasound in Medicine
Liver Disease Diagnosis and Treatment
article

Liver Stiffness Characterization of OGT LKO Mouse Model of Progressive Liver Fibrosis

Marion Régnier, Jean‐Luc Gennisson, Anthony Novell, R Denis, Catherine Postic, Fadila Benhamed, Pierre Monbernard, Gilles Renault, Lenin Chinchilla, Lourdes Massengo
article en

Abstract

Our study confirms that following liver stiffness fibrosis by SWE in a mouse model of liver injury is a valuable tool that correlates with ex vivo findings. This approach facilitates a better understanding of disease progression and therapeutic evaluation in preclinical models of MASH.

Journal of Ultrasound in Medicine
Centre National de la Recherche Scientifique (FR), Inserm (FR), Université Paris Cité (FR), Université Paris-Saclay (FR), Institut Cochin (FR)
Infrastructures en Biologie Santé et Agronomie, Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Institut National Du Cancer, Direction Générale de l’offre de Soins
Openalex Percentile: Top 50%
Liver Disease Diagnosis and Treatment
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