Eco-friendly synthesis of novel enaminonitrile pyridine derivatives: <sup>131</sup> I-radiosynthesis, anticancer investigation and <i>in vivo</i> study in tumour-bearing mice
This work successfully establishes efficient green synthesis routes. Compound <b>7</b> is a potent and selective sustainable theranostic agent, effectively merging green chemistry principles with precision oncology applications for both therapy and diagnosis.
Authors
- Adli A. Selim (ORCID: https://orcid.org/0000-0001-7095-5978)
- Kurls E. Anwer (ORCID: https://orcid.org/0000-0002-3886-6761)
- Basma M. Essa (ORCID: https://orcid.org/0000-0002-3141-9918)
- Safaa S. Shaban (ORCID: https://orcid.org/0000-0002-9327-3467)
- Marwa M. Mehany
- Galal H. Sayed
Institutions
- Ain Shams University (EG)
- Egyptian Atomic Energy Authority (EG)
- Police General Hospital (TH)
- Chemical Synthesis Lab (SG)
Publication Details
- Journal
- Journal of drug targeting
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1080/1061186x.2025.2598323
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00