3-n-Butylphthalide exerts mitochondria-mediated retinal ganglion cell protection and modulates eye–brain axis-related emotional disturbances in glaucoma
These findings offer new insights into the pathophysiological mechanisms of glaucoma and highlight NBP as a promising candidate for neuroprotection and mood regulation via the eye-brain axis, potentially informing future clinical strategies.
Authors
- J. M. Kenny (ORCID: https://orcid.org/0000-0001-6329-3048)
- Xiaodi Zhou
- Rong Rong (ORCID: https://orcid.org/0000-0003-2423-4082)
- Mengling You
- Yixian Liu (ORCID: https://orcid.org/0000-0002-1737-2009)
- Jing Wang (ORCID: https://orcid.org/0000-0001-5921-1804)
- Xiaobo Xia (ORCID: https://orcid.org/0000-0003-1720-7860)
- Jiamiao Liu
Institutions
- Central South University (CN)
- Hunan University of Traditional Chinese Medicine (CN)
- Hunan University (CN)
- National Clinical Research (US)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1097/js9.0000000000004146
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00