Comparison of Continuous Neuromuscular Blocking Agent Titration Strategies in Acute Respiratory Distress Syndrome
In ARDS patients on continuous NMBAs, TOF titration had similar improvement in PaO<sub>2</sub>:FiO<sub>2</sub> ratio at 24 hours and was associated with reduced 28-day mortality, as compared with nonprotocolized VS titration. Prospective studies are warranted to validate and further investigate optimal NMBA titration strategies.
Authors
- Agnes L. Maier (ORCID: https://orcid.org/0009-0006-0767-2039)
- Tia Collier (ORCID: https://orcid.org/0000-0001-6252-8060)
- Rachel Kolar
- Ahmed Shible (ORCID: https://orcid.org/0000-0002-7901-7686)
- Olivia Roberts (ORCID: https://orcid.org/0000-0001-8949-8172)
- Tyler Merritt (ORCID: https://orcid.org/0000-0002-6213-0324)
- Paloma Hauser (ORCID: https://orcid.org/0000-0001-7115-6633)
- Jerry Hung
- Evan Westlake (ORCID: https://orcid.org/0000-0002-8735-7613)
Institutions
- University of North Carolina Health Care (US)
- Erlanger Health System (US)
- Rex Hospital (US)
- Duke University Hospital (US)
Publication Details
- Journal
- Annals of Pharmacotherapy
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1177/10600280251388441
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00