Can the systemic immune-inflammation index be used to differentiate benign and malignant pathologies before transrectal ultrasound-guided prostate biopsy?

Hematological inflammatory parameters before prostate biopsy are not effective markers for distinguishing between biopsy negative and malignant pathologies. The inflammatory markers SII and PLR can be used as diagnostic tools in high-risk prostate cancer patients but cannot be used as markers for the detection of pathologies in low- and intermediate-risk patients.

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Publication Details

Journal
BMC Urology
Published
2025-12-04
DOI
https://doi.org/10.1186/s12894-025-02011-2
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
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article

Can the systemic immune-inflammation index be used to differentiate benign and malignant pathologies before transrectal ultrasound-guided prostate biopsy?

Veli Mert Yazar, Turgay Kaçan, Buğra Bilge Keseroğlu, Yusuf Gökkurt et al.
BMC Urology
Inflammatory Biomarkers in Disease Prognosis
article

Can the systemic immune-inflammation index be used to differentiate benign and malignant pathologies before transrectal ultrasound-guided prostate biopsy?

Veli Mert Yazar, Turgay Kaçan, Buğra Bilge Keseroğlu, Yusuf Gökkurt, Ali Kaan Yıldız, Tolga Karakan, Demirhan Orsan Demir, Ömer Furkan Erbay
article en

Abstract

Hematological inflammatory parameters before prostate biopsy are not effective markers for distinguishing between biopsy negative and malignant pathologies. The inflammatory markers SII and PLR can be used as diagnostic tools in high-risk prostate cancer patients but cannot be used as markers for the detection of pathologies in low- and intermediate-risk patients.

BMC UrologyVol. 26(1)
Bilkent University (TR), Memorial Ankara Hospital (TR), Başkent University Hospital (TR), Afyonkarahisar Sağlık Bilimleri Üniversitesi, Afyon Kocatepe University (TR)
Openalex Percentile: Top 47%
Inflammatory Biomarkers in Disease Prognosis
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Can the systemic immune-inflammation index be used to differentiate benign and malignant pathologies before transrectal ultrasound-guided prostate biopsy? — Veli Mert Yazar, Turgay Kaçan, et al. · BMC Urology (2025) | TGRS Research Map | TGRS