Concept and feasibility of privacy-preserving record linkage of cancer registry data and claims data in Germany: results from the DigiNet study on stage IV non-small cell lung cancer
This study demonstrates the feasibility of PPRL of cancer registry and claims data in a real-world oncological research setting. The concept is transferable to other research contexts requiring secure, identifier-based linkage without disclosure of personal identifiers.
Authors
- Ursula Marschall (ORCID: https://orcid.org/0009-0008-2607-8996)
- Florian Kron (ORCID: https://orcid.org/0000-0003-4907-7490)
- Lizon Fiedler-Lacombe
- Christopher Hampf (ORCID: https://orcid.org/0000-0002-4557-4783)
- Christian Günster (ORCID: https://orcid.org/0000-0003-3085-6259)
- Aleksandra Graw
- Daniela Reil (ORCID: https://orcid.org/0000-0002-0198-9354)
- Sebastian Bartholomäus
- Avron D. Spier (ORCID: https://orcid.org/0009-0001-8256-9756)
- Juergen Wolf (ORCID: https://orcid.org/0000-0001-8833-8812)
- Thomas Ruhnke (ORCID: https://orcid.org/0000-0002-5955-4142)
- Anika Kästner (ORCID: https://orcid.org/0000-0002-1625-4836)
- Stephanie Stock (ORCID: https://orcid.org/0000-0002-1726-9300)
- Renate Kirschner‐Schwabe (ORCID: https://orcid.org/0000-0001-6335-3274)
- Anna Kron (ORCID: https://orcid.org/0000-0002-3047-6486)
- Vanessa Mildenberger
- Wolfgang Hoffmann (ORCID: https://orcid.org/0000-0002-6359-8797)
- Dušan Simić (ORCID: https://orcid.org/0000-0002-7325-9481)
- Jörg Wulff (ORCID: https://orcid.org/0000-0001-8260-3523)
- Neeltje van den Berg (ORCID: https://orcid.org/0000-0001-6965-0544)
- Patrik Dröge (ORCID: https://orcid.org/0000-0003-0263-3154)
- Patrick Naumann (ORCID: https://orcid.org/0000-0001-9814-2151)
- Martin Bialke (ORCID: https://orcid.org/0000-0001-6888-9086)
- Dana Stahl (ORCID: https://orcid.org/0000-0002-4283-4543)
- Andreas Stang (ORCID: https://orcid.org/0000-0001-6363-9061)
- Anna Rasokat (ORCID: https://orcid.org/0009-0008-7850-6374)
- Leonie Eilers
- Jessica Isabel Selig
- Uwe Nußbaum
- Uwe Lührig
- Juliane Mohnke
- Anja Hebbelmann
Institutions
- Universitätsmedizin Greifswald (DE)
- FOM University of Applied Sciences for Economics and Management (DE)
- Universität Greifswald (DE)
- Techniker Krankenkasse (Germany) (DE)
- Düsseldorf University Hospital (DE)
- BARMER GEK (DE)
- National Cancer Registry (IE)
- IKK Classic (DE)
- University Hospital Cologne (DE)
- Wissenschaftliches Institut der AOK (DE)
- Heinrich Heine University Düsseldorf (DE)
- Brandenburg University of Technology Cottbus-Senftenberg (DE)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1007/s00432-025-06384-7
- Primary Topic
- Data Quality and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00