The blocking efficacy and safety of tenofovir disoproxil fumarate tablets on mother-to-child transmission in pregnant women with high serum HBV DNA load: a retrospective cohort study
TDF tablets can prevent MTCT of HBV in pregnant women with high HBV DNA loads. The treatment increases the seroconversion rates of HBV DNA, HBeAg, and HBsAg in mothers and infants, and shows a favorable safety profile without severe adverse outcomes.
Authors
- Shaohua Wang (ORCID: https://orcid.org/0000-0002-6157-7407)
- Qian Liang (ORCID: https://orcid.org/0000-0003-2674-2136)
- Xiaojin Qi
- Lina Song
- Ling Li (ORCID: https://orcid.org/0000-0002-0087-3034)
- Xu Zhang
- Shurong Song (ORCID: https://orcid.org/0009-0002-2110-7897)
- Qing Wei (ORCID: https://orcid.org/0000-0002-8651-3012)
Institutions
- Tianjin Third Central Hospital (CN)
- Cell Technology (China) (HK)
- Tianjin Fire Research Institute (CN)
- Tibet Autonomous Region People's Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1186/s12884-025-08501-3
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00