FIB-4 as an effective screening tool in psoriatic arthritis patients at high-risk for liver disease: a cross-sectional study using FibroScan
CSLD is common in high-risk PsA patients and strongly associated with metabolic risk factors. FIB-4 ≥1.3 had high negative predictive value, supporting its use as a first-line screening tool. Routine MASLD screening using a pathway incorporating FIB-4 followed by FibroScan may inform safer prescribing and improve outcomes.
Authors
- Katya Meridor (ORCID: https://orcid.org/0000-0001-5895-1974)
- Philip Laws (ORCID: https://orcid.org/0000-0002-4628-0699)
- Stephanie R Harrison (ORCID: https://orcid.org/0000-0002-7465-2621)
- Andrew Barr (ORCID: https://orcid.org/0000-0002-5618-8685)
- Richard A. Parker (ORCID: https://orcid.org/0000-0003-4888-8670)
- Helena Marzo‐Ortega (ORCID: https://orcid.org/0000-0002-9683-3407)
- Jane Freeston (ORCID: https://orcid.org/0000-0003-0358-338X)
- Chenchu Chimakurthi (ORCID: https://orcid.org/0000-0002-2797-4855)
- Dennis McGonagle (ORCID: https://orcid.org/0000-0001-7715-8226)
- Claire Vandevelde (ORCID: https://orcid.org/0000-0001-9127-4514)
Institutions
- University of Leeds (GB)
- Leeds Teaching Hospitals NHS Trust (GB)
- Tel Aviv Sourasky Medical Center (IL)
- NIHR Leeds Musculoskeletal Biomedical Research Unit (GB)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1093/rheumatology/keaf640
- Citations
- 3
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.00