Pulmonary vascular and airway changes in previously hospitalised COVID-19 patients: Long-term functional respiratory imaging findings correlate with reduced DLCO
We demonstrate long-term vascular and airway remodelling detected with FRI in previously hospitalised COVID-19 patients and highlight potential mechanisms underlying persistent pulmonary dysfunction and emphasise the need to investigate the underlying pathophysiology to identify potential individualised treatment strategies for this patient group.
Authors
- Malin Nygren‐Bonnier (ORCID: https://orcid.org/0000-0001-6731-8468)
- Hans‐Ulrich Kauczor (ORCID: https://orcid.org/0000-0002-6730-9462)
- Mikael Björnson (ORCID: https://orcid.org/0009-0003-2372-1011)
- Sven Nyrén (ORCID: https://orcid.org/0000-0003-3586-8785)
- Judith Bruchfeld (ORCID: https://orcid.org/0000-0001-5399-0982)
- Anna Kistner (ORCID: https://orcid.org/0000-0002-7942-3211)
- Michael Runold (ORCID: https://orcid.org/0000-0001-7568-2278)
- Magnus Sköld
- Ann-Cathrin Svensson (ORCID: https://orcid.org/0000-0002-0968-1362)
Institutions
- Karolinska University Hospital (SE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Karolinska Institutet (SE)
- German Center for Lung Research (DE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1371/journal.pone.0335075
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00