Efficacy and safety of anticoagulant therapy in patients with sepsis: a meta-analysis of randomized controlled trials
Anticoagulant therapy confers survival benefit in the overall sepsis population despite increased bleeding risk. While improving DIC regression in sepsis-associated DIC, mortality reduction in this subgroup lacked statistical significance. Further research should clarify anticoagulants' role in DIC-specific sepsis management.
Authors
- Wenhao Tang (ORCID: https://orcid.org/0000-0002-4063-0846)
- Jiayu Wu (ORCID: https://orcid.org/0000-0002-6360-857X)
- Qi Wang (ORCID: https://orcid.org/0000-0001-7626-676X)
- Hong Zhang (ORCID: https://orcid.org/0000-0002-1038-973X)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- First Hospital of Jiaxing (CN)
Publication Details
- Journal
- Thrombosis Journal
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1186/s12959-025-00812-x
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00