Comparative immunodiagnostic evaluation of recombinant serine proteases from Trichinella spiralis and Trichinella nativa for early detection of trichinellosis
Recombinant serine proteases rTsp-LE and rTnsp-4E demonstrated high sensitivity, species-specific reactivity, and early antibody detection, outperforming ES antigens. These findings support their potential as reliable candidates for serological assays, contributing to earlier and more accurate trichinellosis diagnosis and improved epidemiological surveillance.
Authors
- Orken Akibekov (ORCID: https://orcid.org/0000-0002-8647-0083)
- Aissarat M. Gajimuradova (ORCID: https://orcid.org/0000-0003-1808-4188)
- Aibek Zhumalin (ORCID: https://orcid.org/0000-0002-8661-7348)
- Fabio Tosini (ORCID: https://orcid.org/0000-0003-1120-5725)
- Ali Aydın (ORCID: https://orcid.org/0000-0002-4931-9843)
- Fariza S. Zhagipar (ORCID: https://orcid.org/0000-0001-5296-1127)
- N. A. Askarova (ORCID: https://orcid.org/0009-0005-3726-4127)
- Aitbay Bulashev (ORCID: https://orcid.org/0000-0002-8427-509X)
- Alfiya Syzdykova (ORCID: https://orcid.org/0000-0002-5405-2469)
- Nurtai Gubaidullin (ORCID: https://orcid.org/0000-0002-8185-714X)
Institutions
- Istituto Superiore di Sanità (IT)
- Istanbul University-Cerrahpaşa (TR)
- S.Seifullin Kazakh Agro Technical University (KZ)
- Istanbul University (TR)
Publication Details
- Journal
- Veterinary World
- Published
- 2025-10-01
- DOI
- https://doi.org/10.14202/vetworld.2025.3243-3254
- Primary Topic
- Parasitic Diseases Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00