Safety of Potassium‐Competitive Acid Blockers Compared With Proton Pump Inhibitors in Patients With Gastroesophageal Reflux Disease and Peptic Ulcer Disease: A Systematic Review and Meta‐Analysis
P-CABs demonstrate a comparable AE risk to PPIs but monitoring for hypergastrinemia and hepatic dysfunction is essential. Further research is required to support safer clinical use.
Authors
- Doo Kyoung Kang (ORCID: https://orcid.org/0000-0002-5397-9334)
- Hankil Lee (ORCID: https://orcid.org/0000-0002-7780-159X)
- Ha‐Lim Jeon (ORCID: https://orcid.org/0000-0002-9429-8711)
- Jae Hyun Kim (ORCID: https://orcid.org/0000-0002-8609-7135)
- Jong-Ho Park (ORCID: https://orcid.org/0000-0001-5883-8322)
- Hyuk Soon Choi (ORCID: https://orcid.org/0000-0002-4343-6950)
- Yusung Jang (ORCID: https://orcid.org/0009-0002-9862-1579)
Institutions
- Ewha Womans University (KR)
- Korea University (KR)
- Jeonbuk State Institute (KR)
- Korea University (JP)
- Ajou University (KR)
- Jeonbuk National University (KR)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1111/jgh.70178
- Citations
- 1
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.81