Short- and Mid-term Cardiac Ventricular Remodelling After Pulmonary Valve Replacement in Adults With Repaired Tetralogy of Fallot
PVR leads to immediate and sustained RV reverse remodelling, with improved systolic function and reinforced biventricular coupling. Early intervention-before RVESVi exceeds 68.5 mL/m2-offers the best chance for RV normalization. Integrating CMR with CPET provides a multiparametric strategy to optimize timing, patient selection, and long-term follow-up in rTOF.
Authors
- Veronica Lisignoli
- Benedetta Leonardi (ORCID: https://orcid.org/0000-0001-6715-3472)
- Eleonora Marinari
- Andrew G. Letizia
- Aurelio Secinaro (ORCID: https://orcid.org/0000-0002-2611-8061)
- Roberta Iacobelli (ORCID: https://orcid.org/0000-0002-0452-3453)
- Veronica Bordonaro (ORCID: https://orcid.org/0000-0002-9011-0793)
- Marin Verrengia
- Fabio Miraldi (ORCID: https://orcid.org/0000-0002-2404-3369)
- Gianluca Brancaccio (ORCID: https://orcid.org/0000-0001-8113-6513)
- Giulia Cafiero (ORCID: https://orcid.org/0000-0001-6180-9338)
- Mara Pilati
- Claudia Montanaro (ORCID: https://orcid.org/0000-0001-8613-8139)
- Ugo Giordano (ORCID: https://orcid.org/0000-0003-0479-5966)
- Victoria D’Inzeo
- Lorenzo Galletti (ORCID: https://orcid.org/0000-0003-2420-1555)
- Lucia Manuri
- Matteo Trezzi (ORCID: https://orcid.org/0000-0002-5867-5823)
- Esposito Claudia
- Chinali Marcello
Institutions
- Bambino Gesù Children's Hospital (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- European Journal of Cardio-Thoracic Surgery
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1093/ejcts/ezaf432
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00