Effects of maternal overnutrition and metabolic challenge in adult life on the histological integrity of the liver and intestinal epithelium in rabbits

These results indicate that exposure to an HFCD during critical developmental windows-both gestation and adulthood-induces significant metabolic disturbances and histological damage in the liver and intestinal epithelium. These effects appear to depend on the timing and duration of dietary exposure.

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Publication Details

Journal
Frontiers in Nutrition
Published
2025-12-04
DOI
https://doi.org/10.3389/fnut.2025.1696494
Primary Topic
Birth, Development, and Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Effects of maternal overnutrition and metabolic challenge in adult life on the histological integrity of the liver and intestinal epithelium in rabbits

Pedro Medina, Rodrigo Montúfar‐Chaveznava, Erika Navarrete, Ivette Caldelas et al.
Frontiers in Nutrition
Birth, Development, and Health
article

Effects of maternal overnutrition and metabolic challenge in adult life on the histological integrity of the liver and intestinal epithelium in rabbits

Pedro Medina, Rodrigo Montúfar‐Chaveznava, Erika Navarrete, Ivette Caldelas, Lucía Carolina Cano, Rosa María Vigueras‐Villaseñor, Juan Pablo Ochoa‐Romo, Georgina Díaz
article en

Abstract

These results indicate that exposure to an HFCD during critical developmental windows-both gestation and adulthood-induces significant metabolic disturbances and histological damage in the liver and intestinal epithelium. These effects appear to depend on the timing and duration of dietary exposure.

Frontiers in NutritionVol. 12
Instituto Nacional de Pediatria (MX), Universidad Autónoma de Madrid (ES), Universidad Politécnica de Madrid (ES), Universidad Nacional Autónoma de México (MX)
Universidad Nacional Autónoma de México, Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México
Openalex Percentile: Top 51%
Birth, Development, and Health
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