When tuberculosis travels: granulomatous tracheitis leading to critical airway stenosis

Tuberculous tracheitis is an uncommon yet serious complication of tuberculosis (TB) infection. The underlying granulomatous inflammation typically results in tracheal stenosis within six months of diagnosis.This report details a case of a woman from Southeast Asia in her mid-40s who presented with chronic weight loss and cough. Imaging demonstrated pulmonary nodules as well as tracheal and oesophageal thickening. Bronchoscopy showed friable, ulcerated tracheal mucosa. Mycobacterium TB was confirmed on microbiological testing. Despite initiating anti-tuberculosis therapy with a standard 4-drug regimen, the patient presented with progressive dyspnoea and inspiratory stridor attributable to severe mid-tracheal stenosis. Multiple bronchoscopic interventions were needed to restore airway patency and prevent recurrent stenosis. This case highlights the importance of prompt recognition, timely intervention and regular follow-up to prevent fibrotic stenosis in tuberculous tracheitis.

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Publication Details

Journal
BMJ Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1136/bcr-2025-267120
Primary Topic
Tracheal and airway disorders
Type
article
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article

When tuberculosis travels: granulomatous tracheitis leading to critical airway stenosis

PAULA ARANGUREN, Laith A Ayasa, Mihir Parikh, Ilana Roberts Krumm
BMJ Case Reports
Tracheal and airway disorders
article

When tuberculosis travels: granulomatous tracheitis leading to critical airway stenosis

PAULA ARANGUREN, Laith A Ayasa, Mihir Parikh, Ilana Roberts Krumm
article en

Abstract

Tuberculous tracheitis is an uncommon yet serious complication of tuberculosis (TB) infection. The underlying granulomatous inflammation typically results in tracheal stenosis within six months of diagnosis.This report details a case of a woman from Southeast Asia in her mid-40s who presented with chronic weight loss and cough. Imaging demonstrated pulmonary nodules as well as tracheal and oesophageal thickening. Bronchoscopy showed friable, ulcerated tracheal mucosa. Mycobacterium TB was confirmed on microbiological testing. Despite initiating anti-tuberculosis therapy with a standard 4-drug regimen, the patient presented with progressive dyspnoea and inspiratory stridor attributable to severe mid-tracheal stenosis. Multiple bronchoscopic interventions were needed to restore airway patency and prevent recurrent stenosis. This case highlights the importance of prompt recognition, timely intervention and regular follow-up to prevent fibrotic stenosis in tuberculous tracheitis.

BMJ Case ReportsVol. 18(12)
Beth Israel Deaconess Medical Center (US), Harvard University (US)
Openalex Percentile: Top 43%
Tracheal and airway disorders
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