Functional profiling of the oral microbiome reveals microbial and oncogenic signatures in never-smoking female patients with oral squamous cell carcinoma
Salivary microbiome alterations, both taxonomic and functional, are associated with OSCC in never-smoking females. These findings suggest a potential microbial contribution to carcinogenesis in this unique patient population and offer novel insights into disease mechanisms.
Authors
- Joo Yong Park (ORCID: https://orcid.org/0000-0002-0969-151X)
- Yong-Seok Choi (ORCID: https://orcid.org/0000-0002-4384-0910)
- Sung Weon Choi (ORCID: https://orcid.org/0000-0002-2038-2881)
- Jae Hee Ko (ORCID: https://orcid.org/0000-0002-5130-3066)
- Zeba Praveen (ORCID: https://orcid.org/0009-0001-4980-6684)
- Sung Min Kim (ORCID: https://orcid.org/0009-0006-4090-3564)
- Yeon-Hee Kim (ORCID: https://orcid.org/0000-0003-4036-4661)
- Jong-Ho Lee (ORCID: https://orcid.org/0000-0002-8843-545X)
- Mi Kyung Kim (ORCID: https://orcid.org/0000-0001-5279-4162)
Institutions
- National Cancer Center (US)
- National Cancer Center (KR)
- Cancer Clinic (US)
Publication Details
- Journal
- Journal of Oral Microbiology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1080/20002297.2025.2594842
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00