Comparing the Bioactive Effects of Ethylenediaminetetraacetic Acid and Maleic Acid on <scp>TGF</scp> ‐β1 Release From Dentine and Dental Pulp Stem Cell Activity
Within the limitations of this study 7% MA performed better than 17% EDTA in promoting TGF-β1 release from dentine, as well as increased DPSC responses related to cell proliferation, migration, and mineralisation. These findings indicate that 7% MA may be a promising dentine conditioning agent during VPT procedures.
Authors
- Henry F. Duncan (ORCID: https://orcid.org/0000-0001-8690-2379)
- Rajkumar Narkedamalli (ORCID: https://orcid.org/0000-0002-8336-9107)
- Vinutha Bhat (ORCID: https://orcid.org/0000-0002-9457-9492)
- Vijetha Shenoy Belle (ORCID: https://orcid.org/0000-0003-3319-9661)
- Nidambur Vasudev Ballal (ORCID: https://orcid.org/0000-0002-2208-9443)
- Anandh Dhanushkodi (ORCID: https://orcid.org/0000-0002-3443-4697)
- Sundeep Mata (ORCID: https://orcid.org/0000-0002-9772-0279)
- Adithya Subramanya (ORCID: https://orcid.org/0009-0005-0635-0436)
Institutions
- Manipal Academy of Higher Education (IN)
- Trinity College Dublin (IE)
- Dublin Dental University Hospital (IE)
- Kasturba Medical College, Manipal (IN)
Publication Details
- Journal
- International Endodontic Journal
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1111/iej.70075
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00