The microbial metabolite desaminotyrosine is a potent antiobesity agent with potential effects on white adipose tissue remodeling in mice
Collectively, these data demonstrate that DAT is a potent antiobesity agent with potential effects on white adipose tissue remodeling. This study provides a novel pharmacological strategy targeting white adipocyte plasticity for treating metabolic disorders.
Authors
- Qiuchong Chen
- Huimin Bu
- Wanpeng Cheng
- Yugang Wang (ORCID: https://orcid.org/0000-0002-0709-1924)
- Kuiyang Zheng (ORCID: https://orcid.org/0000-0002-1896-7485)
- Zhuan-Zhuan Liu (ORCID: https://orcid.org/0000-0002-9453-9714)
- Yanbo Kou (ORCID: https://orcid.org/0000-0002-8794-4711)
- Guosheng Fu (ORCID: https://orcid.org/0000-0001-7027-0717)
- Yaoyao Xiang
- Yanxia Wei (ORCID: https://orcid.org/0000-0003-2706-957X)
- Haohan Huang
- Longxiang Liao
Institutions
- Xuzhou Medical College (CN)
- Jiangsu Food and Pharmaceutical Science College (CN)
- Institute of Infection and Immunity (CA)
Publication Details
- Journal
- Gut Microbes
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1080/19490976.2025.2587400
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00