Association between bone marrow adipose tissue, abdominal adipose tissue distribution, and volumetric bone mineral density in the Chinese adult population: a retrospective cohort study
Our results indicated a negative association between BMAT and BMD. The association between abdominal adipose tissue distribution and BMD was dual; there was a positive association between SAT and BMD and a negative association between VAT and BMD. These findings suggest that the distribution of abdominal adipose tissue, particularly visceral adipose tissue accumulation, should be prioritized over total body weight in considerations of bone health.
Authors
- Wenmin Guan (ORCID: https://orcid.org/0000-0003-2856-5196)
- Fengxia Yu (ORCID: https://orcid.org/0000-0002-3970-3008)
- Wei Zhu (ORCID: https://orcid.org/0000-0001-7190-7476)
- Zhenchang Wang (ORCID: https://orcid.org/0000-0001-8190-6469)
- Bo-Xin Chen
- Yue Lu (ORCID: https://orcid.org/0000-0002-5479-9095)
- Peng Zhang (ORCID: https://orcid.org/0000-0003-4278-0036)
- Weihua Li (ORCID: https://orcid.org/0009-0006-2163-3335)
- Jingyi Liu (ORCID: https://orcid.org/0000-0001-7123-0119)
- Hongxia Yin (ORCID: https://orcid.org/0000-0003-2804-1253)
- Zhi‐Jun Zhu
- Xiaoqing Yuan (ORCID: https://orcid.org/0009-0005-8965-686X)
- Wei Lin (ORCID: https://orcid.org/0009-0006-5068-4502)
- Jia Li (ORCID: https://orcid.org/0000-0002-7191-1181)
Institutions
- Capital Medical University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-12-04
- DOI
- https://doi.org/10.7717/peerj.20446
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Beijing Science and Technology Planning Project