Dramatic Response to Palliative Radiotherapy in Advanced Eyelid Squamous Cell Carcinoma: A Case Report

Conjunctival squamous cell carcinoma (SCC) is a rare ocular malignancy that can occasionally present. We describe the case of an older patient who presented with a massive orbital lesion that caused severe functional and cosmetic impairments. Palliative radiotherapy of the orbital mass resulted in remarkable tumor regression and symptomatic relief. After 18 months of follow-up, the patient remained clinically stable without regrowth of the primary lesion. This case highlights the potential of palliative radiotherapy to achieve durable local control and meaningful improvement in the quality of life, even in advanced conjunctival SCC.