Unprecedented 1,2-mesityl shift for the synthesis of iridafurans
The reactivity of tertiary propargylic alcohols bearing a mesityl substituent with [IrCp*Cl(NCMe)(PMe<sub>3</sub>)]PF<sub>6</sub> has revealed a previously unreported 1,2-mesityl rearrangement, leading to the formation of α-iridafuran complexes. Comparative analysis with the rhodium analogue as well as different substituents at the propargylic alcohol highlights the unique reactivity of the iridium system, the key role of the mesityl group and the importance of substituent topology.
Authors
- S. Bolaño (ORCID: https://orcid.org/0000-0002-5013-9831)
- Nicolás Otero (ORCID: https://orcid.org/0000-0002-5313-7970)
- Ángeles Peña‐Gallego (ORCID: https://orcid.org/0000-0002-6898-8305)
- María Talavera (ORCID: https://orcid.org/0000-0003-2635-4133)
- Antonio Bermejo Gómez (ORCID: https://orcid.org/0000-0002-1333-7740)
Institutions
- Universidade de Vigo (ES)
Publication Details
- Journal
- Dalton Transactions
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1039/d5dt02755a
- Primary Topic
- Catalytic Alkyne Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidade de Vigo
- Xunta de Galicia
- European Regional Development Fund